Tongye Shen
tshen@ucsd.edu
UC San Diego
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Biophysics theory
Biological systems function in noisy environments. To understand how the
signaling information is propagated and how large scale
structure form in the cells are major challenges of the
statistical physics requiring going beyond equilibrium theory.
From a physical point of view, these aspects of cell biology
can be formulated as questions of the stability of attractor
states and the dynamics of transitions among such states in a
manybody system. I will show how a common set of techniques
(some "partition function" based and others dynamic
operator based) can be used to study the statistical
attractors of nonequilibrium biological systems. These
methods, somewhat analogous to ones from other fields of
physics, are illustrated with examples from biomolecule
folding and the far-from-equilibrium structure and motion of
cells. I will also mention some unique challenges faced here
which, if resolved, may yield benefits for work in other
fields.
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